The computational identification of missense mutation in CST3 (CYSTATIN 3 or CYSTATIN C) gene has been done in the present study.The missense mutations in the CST3 gene will leads to hereditary cerebral amyloid angiopathy The initiation of Knitwear the analysis was done with SIFT followed by POLYPHEN-2 and I-Mutant 2.0 using 24 variants of CST3 gen
Fabrication and Characterization of Chitosan/Poly(Lactic-Co-glycolic Acid) Core-Shell Nanoparticles by Coaxial Electrospray Technology for Dual Delivery of Natamycin and Clotrimazole
Natamycin (NAT) is the drug of choice for the treatment of fungal keratitis (FK).However, its inherent shortcomings, such as poor solubility, high dosing frequency, and long treatment cycle, need to be urgently addressed by designing a new delivery to widen its clinical utility.Growing research has confirmed that clotrimazole (CLZ) plays a signific